Gastric adenocarcinoma in patients 40 years of age or younger

摘要: BACKGROUND : Gastric adenocarcinoma is considered a disease of the middle aged and elderly has been infrequently reported in patients under 40 years age. The purpose this study was to determine proportion young diagnosed with gastric compare demographic, clinical pathologic features younger older adenocarcinoma. METHODS A retrospective cohort using tumor registry records all from 1982 through 1996 at public teaching hospital. Demographic, clinical, comparisons were made between than 41 age race- sex-matched RESULTS Thirty 203 (15%) cases less (range 23 40). Male female ratio 1 :1. Young more likely be black (33% versus 17%, P = 0.04) Both presented advanced disease, nearly half each group having metastases. Twelve 29 (41%) operated on without histologic diagnosis contrast only patient (P < 0.001). One 30 (3%) alive 39 months following gastrectomy. Twenty died remaining 9 lost follow-up, known residual or recurrent disease. Six-month survival (23%) (42%) 0.14). have diffuse histology (80% 55%, 0.12). Overt infection Helicobacter pylori uncommon both groups. CONCLUSIONS accounted for an unusually high our significantly accurate preoperative diagnosis. had poor survival. poorer 6-month survival, suggesting aggressive variety group.