作者: Silvano Esposito , Sebastiano Leone
DOI: 10.1016/J.IJANTIMICAG.2006.10.017
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摘要: Between 5 and 10% of patients admitted to acute care hospitals acquire one or more infections, the risks have steadily increased during recent decades. Three types infection account for than 60% all nosocomial infections: pneumonia, urinary tract primary bloodstream infection, them associated with use medical devices. Nearly 70% infections are due micro-organisms resistant antibiotics (multidrug MDR). A higher incidence inappropriate antibiotic therapy is expected when caused by antibiotic-resistant initial empirical therapies, further need modify substantially increases mortality risk. Despite new antibacterial agents such as linezolid, also tigecycline daptomycin, now being available treatment MDR micro-organisms, best strategy improving cure rate minimising development resistance, probably remains infectious disease specialist consultation.