The Cytoskeletal System of Nucleated Erythrocytes

摘要: Publisher Summary This chapter focuses on cytoskeleton formation and function of the marginal band (MB) microtubules (MTs). It highlights cytological, ultrastructural, molecular observations nonmammalian erythrocytes. The also discusses comparative work primitive nucleated erythrocytes in developing mammals. All mature vertebrates contain bands (MBs). MB is principally a hooplike continuous microtubule (MT) bundle located close to plasma membrane plane flattening. For vertebrates, thickness light microscope MT number per electron microscopic (EM) cross section are positively correlated with cell size. flexible both situ after isolation—that is, it can bend twist without breaking. Tubulin major component MBs. was found constitute 1% total protein, less than one-half MB. assembly long MTs typical MBs might be regulated by tubulin oligomer pool, limiting nucleation rate accounting for at least some non-MB cell.