Energy metabolism disorders in rare and common diseases. Toward bioenergetic modulation therapy and the training of a new generation of European scientists

摘要: Abstract Energy metabolism alterations are found in a large number of rare and common diseases genetic or environmental origin. The patients that could benefit from bioenergetic modulation therapy (BIOMET) is therefore very important includes individuals with pathologies as diverse mitochondrial diseases, acute coronary syndrome, chronic kidney disease, asthma even cancer. Although, the alteration energy disease specific sometimes patient specific, strategies for BIOMET be target series regulatory mechanisms discussed this article. An excellent training scientists field metabolism, related human drug discovery also crucial to form young generation MDs, PHDs Pharma CRO-group leaders who will discover novel personalized medicines, through pharmacology, genetics, nutrition adapted exercise training. Mitochondrial European Educational Training (MEET) consortium was created pursue goal, we dedicated here special issue Organelle Focus (OiF) highlight their objectives. A total 10 OiFs articles constitute Directed Issue on Medicine. As part editorial article, asked timely questions PR. Jan W. Smeitink, professor Medicine CEO Khondrion, medicine company. He shared us his objectives study identification future treatments. This article entitled: Metabolism Disorders Therapies.