Free radical scavenging ability and antioxidant efficiency of curcumin and its substituted analogue.

摘要: Abstract Free radical reactions of curcumin and its ethoxy substituted derivative (C1) 1,7-bis-(4-hydroxy-3-ethoxy phenyl)-1,6-heptadiene-3,5-dione have been studied using a pulse radiolysis technique in homogeneous aqueous–organic solutions like acetonitrile–water isopropanol–water mixtures, as well neutral TX-100 cationic CTAB micellar solutions. The phenoxyl radicals or C1 were generated by one-electron transfer to several oxidants N 3 · , Br 2 −·· CCl O glutathione which exhibit absorption from 300–600-nm wavelength region with the maximum at 490–500 nm. Other important properties such extinction coefficient, lifetime their formation decay rate constants also determined these systems. antioxidant property estimated terms ability inhibit lipid peroxidation liposomes trolox equivalent capacity (TEAC). results compared α-tocopherol.