作者: Éric Wersinger
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摘要: PROBLEM TO BE SOLVED: To provide novel methods for treating tinnitus.SOLUTION: The invention provides a histamine type 4 receptor (H4R) inhibitor use in treatment of tinnitus. Preferably, the that inhibits H4R protein expression and/or activity gene is 2-aminopyrimidine derivatives compound, pyrimidine quinazoline sulfonamide bicyclic heteroaryl-substituted imidazole thieno-pyrimidine furo-pyrimidine mequitazine and like.SELECTED DRAWING: None