The Effect of the Duration of Anticoagulation and Other Risk Factors on the Recurrence of Venous Thromboembolisms

摘要: BACKGROUND In order to find the optimal balance of anticoagulation, avoiding recurrent events as well major hemorrhage, it is important know impact different risk factors over time. METHODS Based on a randomized, multicenter trial durations anticoagulation after first episode venous thromboembolism, probability recurrence 6 years follow-up was analyzed. The contribution site thrombus, nature triggering factor and presence cardiolipin antibodies also calculated. RESULTS There cumulative 4 5% per year, which continues through year index event, independent initial duration anticoagulation. Deep vein thrombosis proximal knee joint or symptomatic pulmonary embolism confers that higher than distal but equal when permanent unknown. combination deep permanent/unknown increases risk, generates an additional in all subgroups. CONCLUSION It necessary tailor individually, according factors.