Recent Updates on Epigenetic Biomarkers for Prostate Cancer
作者： Karen Chiam , Tanya Kate Day , Tina Bianco-Miotto
DOI: 10.1007/978-94-007-6612-9_8
关键词:
摘要: Epigenetics refers to DNA methylation, histone modifications and microRNAs these epigenetic are extensively investigated as potential biomarkers for cancer. Characterizing genome wide changes involved in prostate cancer development progression will not only identify novel therapeutic targets, since some reversible, but also highlight which can be used biomarkers. Epigenetic relatively stable easy measure peripheral samples like blood urine, further highlighting their importance powerful tools assessing patient diagnosis prognosis. In this review, we outline how have been diagnosis, prognosis monitoring response We review may more sensitive specific than current serum markers the possibility that combining different enhance diagnostic prognostic ability of As epigenome studies continue performed larger cohorts, soon tumorigenesis with resultant identification new targets robust
springer.com
sci-hub.se 参考文章(117)
Valeria Coppola, Ruggero De Maria, Désirée Bonci, MicroRNAs and prostate cancer Endocrine-related Cancer. ,vol. 17, ,(2010) , 10.1677/ERC-09-0172
S. A. Tomlins, S. M. J. Aubin, J. Siddiqui, R. J. Lonigro, L. Sefton-Miller, S. Miick, S. Williamsen, P. Hodge, J. Meinke, A. Blase, Y. Penabella, J. R. Day, R. Varambally, B. Han, D. Wood, L. Wang, M. G. Sanda, M. A. Rubin, D. R. Rhodes, B. Hollenbeck, K. Sakamoto, J. L. Silberstein, Y. Fradet, J. B. Amberson, S. Meyers, N. Palanisamy, H. Rittenhouse, J. T. Wei, J. Groskopf, A. M. Chinnaiyan, Urine TMPRSS2:ERG Fusion Transcript Stratifies Prostate Cancer Risk in Men with Elevated Serum PSA Science Translational Medicine. ,vol. 3, ,(2011) , 10.1126/SCITRANSLMED.3001970
J. H. Kim, S. M. Dhanasekaran, J. R. Prensner, X. Cao, D. Robinson, S. Kalyana-Sundaram, C. Huang, S. Shankar, X. Jing, M. Iyer, M. Hu, L. Sam, C. Grasso, C. A. Maher, N. Palanisamy, R. Mehra, H. D. Kominsky, J. Siddiqui, J. Yu, Z. S. Qin, A. M. Chinnaiyan, Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer Genome Research. ,vol. 21, pp. 1028- 1041 ,(2011) , 10.1101/GR.119347.110
P. S. Mitchell, R. K. Parkin, E. M. Kroh, B. R. Fritz, S. K. Wyman, E. L. Pogosova-Agadjanyan, A. Peterson, J. Noteboom, K. C. O'Briant, A. Allen, D. W. Lin, N. Urban, C. W. Drescher, B. S. Knudsen, D. L. Stirewalt, R. Gentleman, R. L. Vessella, P. S. Nelson, D. B. Martin, M. Tewari, Circulating microRNAs as stable blood-based markers for cancer detection Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 10513- 10518 ,(2008) , 10.1073/PNAS.0804549105
Geert J.L.H. van Leenders, Danny Dukers, Daphne Hessels, Susan W.M. van den Kieboom, Christina A. Hulsbergen, J. Alfred Witjes, Arie P. Otte, Chris J. Meijer, Frank M. Raaphorst, Polycomb-Group Oncogenes EZH2, BMI1, and RING1 Are Overexpressed in Prostate Cancer With Adverse Pathologic and Clinical Features European Urology. ,vol. 52, pp. 455- 463 ,(2007) , 10.1016/J.EURURO.2006.11.020
Y. Pang, C. Y. F. Young, H. Yuan, MicroRNAs and prostate cancer. Acta Biochimica et Biophysica Sinica. ,vol. 42, pp. 363- 369 ,(2010) , 10.1093/ABBS/GMQ038
Patrick J. Bastian, Ganesh S. Palapattu, Xiaohui Lin, Srinivasan Yegnasubramanian, Leslie A. Mangold, Bruce Trock, Mario A. Eisenberger, Alan W. Partin, William G. Nelson, Preoperative serum DNA GSTP1 CpG island hypermethylation and the risk of early prostate-specific antigen recurrence following radical prostatectomy. Clinical Cancer Research. ,vol. 11, pp. 4037- 4043 ,(2005) , 10.1158/1078-0432.CCR-04-2446
Jong Y. Park, Promoter hypermethylation in prostate cancer. Cancer Control. ,vol. 17, pp. 245- 255 ,(2010) , 10.1177/107327481001700405
Jindan Yu, Jianjun Yu, Daniel R. Rhodes, Scott A. Tomlins, Xuhong Cao, Guoan Chen, Rohit Mehra, Xiaoju Wang, Debashis Ghosh, Rajal B. Shah, Sooryanarayana Varambally, Kenneth J. Pienta, Arul M. Chinnaiyan, A polycomb repression signature in metastatic prostate cancer predicts cancer outcome. Cancer Research. ,vol. 67, pp. 10657- 10663 ,(2007) , 10.1158/0008-5472.CAN-07-2498
Kasper Daniel Hansen, Winston Timp, Héctor Corrada Bravo, Sarven Sabunciyan, Benjamin Langmead, Oliver G McDonald, Bo Wen, Hao Wu, Yun Liu, Dinh Diep, Eirikur Briem, Kun Zhang, Rafael A Irizarry, Andrew P Feinberg, Increased methylation variation in epigenetic domains across cancer types Nature Genetics. ,vol. 43, pp. 768- 775 ,(2011) , 10.1038/NG.865