Benzylsulfonic acid functionalized mesoporous Zr-TMS catalysts: An efficient and recyclable catalyst for the preparation of coumarin derivatives by Pechmann condensation reaction

摘要: Abstract Benzylsulfonic acid functionalized mesoporous Zr-TMS (Zr-TMS-BSA, Zr-TMS, zirconia based transition metal oxide molecular sieves) catalyst is used as an alternative to conventional catalysts in the von Pechmann condensation of aromatic alcohols with ethyl acetoacetate leading formation coumarin derivatives solvent free condition at 150 °C. Three types coumarins, 7-hydroxy-4-methylcoumarin (β-methylumbelliferone), 7-methoxy-4-methylcoumarin (Methyl-4-methylumbelliferyl ether) and 7,8-benzo-4-methylcoumarin have been prepared using resorcinol, 3-methoxyphenol 1-naphthol, respectively. The catalytic activity recycle studies all three reactions proved superior performance catalyst. Further products were confirmed by GC, elemental analysis, melting point NMR techniques. Finally, probable mechanism for Zr-TMS-BSA has reported.