Carrot cells: a pioneering platform for biopharmaceuticals production.

作者: Sergio Rosales-Mendoza , Marlene Anahí Tello-Olea

DOI: 10.1007/S12033-014-9837-Y

关键词:

摘要: Carrot (Daucus carota L.) is of importance in the molecular farming field as it constitutes first plant species approved to produce biopharmaceuticals for human use. In this review, features that make carrot an advantageous are analyzed and a description developments achieved with crop thus far presented. A guide genetic transformation procedures also included. The state art comprises ten vaccine prototypes against Measles virus, Hepatitis B Human immunodeficiency Yersinia pestis, Chlamydia trachomatis, Mycobacterium tuberculosis, enterotoxigenic Escherichia coli, Corynebacterium diphtheria/Clostridium tetani/Bordetella pertussis, Helicobacter pylori; well case glucocerebrosidase, enzyme used replacement therapy, other therapeutics. Perspectives these envisioned innovations proposed such use transplastomic technologies-, hairy roots-, viral expression-based systems improve yields develop new products derived from species.

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