Septic shock patients with adequate tissue perfusion parameters still need the recommended minimal Mean Arterial Pressure: For sure

Jing-Yuan Xu, Si-Qing Ma, Chun Pan, Hong-Li He, Shi-Xia Cai, Shu-Ling Hu, Ai-Ran Liu, Ling Liu, Ying-Zi Huang, Feng-Mei Guo, Yi Yang, Hai-Bo Qiu, A high mean arterial pressure target is associated with improved microcirculation in septic shock patients with previous hypertension: a prospective open label study Critical Care. ,vol. 19, pp. 130- 130 ,(2015) , 10.1186/S13054-015-0866-0

Maurizio Cecconi, Daniel De Backer, Massimo Antonelli, Richard Beale, Jan Bakker, Christoph Hofer, Roman Jaeschke, Alexandre Mebazaa, Michael R. Pinsky, Jean Louis Teboul, Jean Louis Vincent, Andrew Rhodes, Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine Intensive Care Medicine. ,vol. 40, pp. 1795- 1815 ,(2014) , 10.1007/S00134-014-3525-Z

Pierre Asfar, Ferhat Meziani, Jean-François Hamel, Fabien Grelon, Bruno Megarbane, Nadia Anguel, Jean-Paul Mira, Pierre-François Dequin, Soizic Gergaud, Nicolas Weiss, François Legay, Yves Le Tulzo, Marie Conrad, René Robert, Frédéric Gonzalez, Christophe Guitton, Fabienne Tamion, Jean-Marie Tonnelier, Pierre Guezennec, Thierry Van Der Linden, Antoine Vieillard-Baron, Eric Mariotte, Gaël Pradel, Olivier Lesieur, Jean-Damien Ricard, Fabien Hervé, Damien Du Cheyron, Claude Guerin, Alain Mercat, Jean-Louis Teboul, Peter Radermacher, None, High versus Low Blood-Pressure Target in Patients with Septic Shock The New England Journal of Medicine. ,vol. 370, pp. 1583- 1593 ,(2014) , 10.1056/NEJMOA1312173

Thiago Corrêa, Madhusudanarao Vuda, Jukka Takala, Siamak Djafarzadeh, Eliézer Silva, Stephan Jakob, Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function Critical Care. ,vol. 17, pp. 1- 12 ,(2013) , 10.1186/CC12495

Aurélie Thooft, Raphaël Favory, Diamantino Salgado, Fabio S Taccone, Katia Donadello, Daniel De Backer, Jacques Creteur, Jean-Louis Vincent, Effects of changes in arterial pressure on organ perfusion during septic shock Critical Care. ,vol. 15, pp. 1- 8 ,(2011) , 10.1186/CC10462

Arnaldo Dubin, Mario O Pozo, Christian A Casabella, Fernando Pálizas, Gastón Murias, Miriam C Moseinco, Vanina S Kanoore Edul, Fernando Pálizas, Elisa Estenssoro, Can Ince, Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study Critical Care. ,vol. 13, pp. 1- 8 ,(2009) , 10.1186/CC7922

Mervyn Singer, Clifford S Deutschman, Christopher Warren Seymour, Manu Shankar-Hari, Djillali Annane, Michael Bauer, Rinaldo Bellomo, Gordon R Bernard, Jean-Daniel Chiche, Craig M Coopersmith, Richard S Hotchkiss, Mitchell M Levy, John C Marshall, Greg S Martin, Steven M Opal, Gordon D Rubenfeld, Tom van der Poll, Jean-Louis Vincent, Derek C Angus, None, The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) JAMA. ,vol. 315, pp. 801- 810 ,(2016) , 10.1001/JAMA.2016.0287

Pierre-Grégoire Guinot, Dan Longrois, Said Kamel, Emmanuel Lorne, Hervé Dupont, Ventriculo-Arterial Coupling Analysis Predicts the Hemodynamic Response to Norepinephrine in Hypotensive Postoperative Patients: A Prospective Observational Study. Critical Care Medicine. ,vol. 46, ,(2018) , 10.1097/CCM.0000000000002772

O. Hamzaoui, M. Jozwiak, T. Geffriaud, B. Sztrymf, D. Prat, F. Jacobs, X. Monnet, P. Trouiller, C. Richard, J.L. Teboul, Norepinephrine exerts an inotropic effect during the early phase of human septic shock. BJA: British Journal of Anaesthesia. ,vol. 120, pp. 517- 524 ,(2017) , 10.1016/J.BJA.2017.11.065

Kamal Maheshwari, Brian H. Nathanson, Sibyl H. Munson, Victor Khangulov, Mitali Stevens, Hussain Badani, Ashish K. Khanna, Daniel I. Sessler, The relationship between ICU hypotension and in-hospital mortality and morbidity in septic patients. Intensive Care Medicine. ,vol. 44, pp. 857- 867 ,(2018) , 10.1007/S00134-018-5218-5