Opioid peptide-like immunoreactivity localized in GABAErgic neurons of rat neostriatum and central amygdaloid nucleus.
作者： W.H. Oertel , G. Riethmüller , E. Mugnaini , D.E. Schmechel , A. Weindl
DOI: 10.1016/0024-3205(83)90447-2
关键词:
摘要: Abstract Opioid peptide-like (OPL)-immunoreactivity and (the GABA-biosynthetic enzyme) glutamic acid decarboxylase-like (GAD)-immunoreactivity were localized in rat neostriatum central amygdaloid nucleus (ACE) using a polyclonal sheep antiserum to brain GAD monoclonal mouse antibody the N-terminus of β-endorphin (3-E7) as primary antisera. PAP-immunohistochemistry revealed GAD-immunoreactivity majority neurons ACE. OPL-immunoreactivity was observed numerous ACE, but only few neostriatal nerve cells. In double immunofluorescence same section OPL- colocalized medium size cells neostriatum, The existence opioid peptide containing GABAergic ACE is demonstrated.
elsevier.com
sci-hub.se 参考文章(15)
M DiFiglia, N Aronin, JB Martin, Light and electron microscopic localization of immunoreactive Leu-enkephalin in the monkey basal ganglia. The Journal of Neuroscience. ,vol. 2, pp. 303- 320 ,(1982) , 10.1523/JNEUROSCI.02-03-00303.1982
James C. W. Finley, Jerome L. Maderdrut, Peter Petrusz, The immunocytochemical localization of enkephalin in the central nervous system of the rat The Journal of Comparative Neurology. ,vol. 198, pp. 541- 565 ,(1981) , 10.1002/CNE.901980402
W.H. Oertel, M.L. Tappaz, A. Berod, E. Mugnaini, Two-color immunohistochemistry for dopamine and GABA neurons in rat substantia nigra and zona incerta. Brain Research Bulletin. ,vol. 9, pp. 463- 474 ,(1982) , 10.1016/0361-9230(82)90155-1
W.H. Oertel, D.E. Schmechel, E. Mugnaini, M.L. Tappaz, I.J. Kopin, Immunocytochemical localization of glutamate decar☐ylase in rat cerebellum with a new antiserum Neuroscience. ,vol. 6, pp. 2715- 2735 ,(1981) , 10.1016/0306-4522(81)90115-9
M.R. Brann, P.C. Emson, Microiontophoretic injection of fluorescent tracer combined with simultaneous immunofluorescent histochemistry for the demonstration of efferents from the caudate-putamen projecting to the globus pallidus. Neuroscience Letters. ,vol. 16, pp. 61- 65 ,(1980) , 10.1016/0304-3940(80)90101-9
Steven Vincent, Tomas Hökfelt, Ingrid Christensson, Lars Terenius, Immunohistochemical evidence for a dynorphin immunoreactive striato-nigral pathway European Journal of Pharmacology. ,vol. 85, pp. 251- 252 ,(1982) , 10.1016/0014-2999(82)90477-0
Henry Khachaturian, Stanley J. Watson, Michael E. Lewis, David Coy, Avram Goldstein, Huda Akil, Dynorphin Immunocytochemistry in the Rat Central Nervous System Peptides. ,vol. 3, pp. 941- 954 ,(1982) , 10.1016/0196-9781(82)90063-8
Christian Gramsch, Tommaso Meo, Gert Riethmüller, Albert Herz, Binding Characteristics of a Monoclonal β-Endorphin Antibody Recognizing the N-Terminus of Opioid Peptides Journal of Neurochemistry. ,vol. 40, pp. 1220- 1226 ,(1983) , 10.1111/J.1471-4159.1983.TB13560.X
Charles E. Ribak, James E. Vaughn, Kihachi Saito, Robert Barber, Eugene Roberts, Immunocytochemical localization of glutamate decarboxylase in rat substantia nigra Brain Research. ,vol. 116, pp. 287- 298 ,(1976) , 10.1016/0006-8993(76)90906-9
Madhabananda Sar, Walter E. Stumpf, Richard J. Miller, Kwen-Jen Chang, Pedro Cuatrecasas, Immunohistochemical localization of enkephalin in rat brain and spinal cord. The Journal of Comparative Neurology. ,vol. 182, pp. 17- 37 ,(1978) , 10.1002/CNE.901820103