Study of HLA antigens in familial and sporadic rheumatoid arthritis.

作者: M. A. Khan , G. Kammer , C. L. Dejelo , I. Kushner , W. E. Braun

DOI: 10.1111/J.1399-0039.1983.TB00369.X

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摘要: Patients with familial and non-familial (sporadic) forms of rheumatoid arthritis (RA) were studied to investigate possible HLA heterogeneity. HLA-DR4 was present in 75% 59% sporadic RA patients. The frequency distribution A2, B8, B27, Cw3 DR3 differed somewhat between the two groups; however, differences not statistically significant this small group Studies a larger number patients are indicated explore possibility genetic subgroups RA.

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