Design of porphyrin-based conjugated microporous polymers with enhanced singlet oxygen productivity

摘要: Novel non-toxic materials with antimicrobial surfaces are needed for medicinal applications. Potential alternatives bacterial inactivation include that produce singlet oxygen, O2(1Δg), a short-lived, highly oxidative, and cytotoxic species. We synthesized promising group of materials, porphyrin-based conjugated microporous polymers (CMPs), which effectively generate O2(1Δg) under visible light irradiation. CMPs were rationally designed to maximize production. A strategy based on three-dimensional frameworks allowed the immediate environment porphyrin units be tuned their structure–property relationships elucidated. investigated photophysical photochemical properties compared them metal–organic frameworks. In general, production activity correlated neither surface area nor pore volume. The novel displayed high production, stable in organic solvents, did not undergo measurable photobleaching.