Gene expression. The amazing demethylase.
作者： Howard Cedar , Gregory L. Verdine
DOI: 10.1038/17492
关键词:
摘要: DNA methylation is important for repressing gene expression, and much known about how methyl groups are added to DNA. But little has been done work out they're taken off again. Now, a hitherto unknown cloned, which encodes protein that seems catalyse demethylation by directly removing the from 5-methyl-cytosine.
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Richard Z. Chen, Ulf Pettersson, Caroline Beard, Laurie Jackson-Grusby, Rudolf Jaenisch, DNA hypomethylation leads to elevated mutation rates Nature. ,vol. 395, pp. 89- 93 ,(1998) , 10.1038/25779
Sanjoy K. Bhattacharya, Shyam Ramchandani, Nadia Cervoni, Moshe Szyf, A mammalian protein with specific demethylase activity for mCpG DNA Nature. ,vol. 397, pp. 579- 583 ,(1999) , 10.1038/17533