Cancer recurrence and lethality are enabled by enhanced survival and reversible cell cycle arrest of polyaneuploid cells.

作者: K. J. Pienta , E. U. Hammarlund , E. U. Hammarlund , R. M. Axelrod , J. S. Brown

DOI: 10.1073/PNAS.2020838118

关键词:

摘要: … polyploid programs, even when cell division is blocked (76). It is noteworthy that polyploid cells … genomic material, but by their increased cellular contents and sheer size (127, 128). …

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