Occupational Exposure to Solvents and Risk of Non-Hodgkin Lymphoma in Connecticut Women

摘要: A population-based case-control study involving 601 incident cases of non-Hodgkin lymphoma (NHL) and 717 controls was conducted in 1996-2000 among Connecticut women to examine associations with exposure organic solvents. job-exposure matrix used assess occupational exposures. Increased risk NHL associated chlorinated solvents (odds ratio (OR) = 1.4, 95% confidence interval (CI): 1.1, 1.8) carbon tetrachloride (OR 2.3, CI: 1.3, 4.0). Those ever exposed any solvent work settings had a borderline increased 1.0, 1.6); moreover, significantly observed for those average probability at medium-high level 1.5, 1.9). also found formaldehyde 1.7) settings. Risk increasing intensity (P 0.01), < cumulative 0.01) 0.02) 0.02). Analyses by subtype showed pattern diffuse large B-cell similar that overall NHL, stronger evidence an association benzene exposure. Results suggest women.