Corticosterone: a critical factor in an opioid form of stress-induced analgesia

作者: A. MacLennan , R. Drugan , R. Hyson , S. Maier , J Madden

DOI: 10.1126/SCIENCE.7063862

关键词:

摘要: The finding that some opioid-mediated forms of stress-induced analgesia are antagonized by hypophysectomy and dexamethasone has led to the suggestion beta-endorphin, released from pituitary, may mediate these analgesic reactions. "Long-term analgesia" (an form analgesia), which is blocked hypophysectomy, was also adrenalectomy reinstated with corticosterone therapy. Corticosterone proposed play a permissive role in long-term be critical hormone mediating this phenomenon.

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