Ultrasound guided FNA of thyroid performed by cytopathologists enhances Bethesda diagnostic value.

作者: Maoxin Wu , YoonSun Choi , Zesong Zhang , Quisheng Si , Fadi Salem

DOI: 10.1002/DC.23544

关键词:

摘要: Background Ultrasound (US) guided fine needle aspiration (FNA) biopsy of thyroid are examined and reported by cytopathologists based usually on The Bethesda System for Reporting Thyroid Cytopathology (BTC) regardless the procedure's performers. This study is designed to determine whether there any performer-dependent difference. Methods Six hundred fifty-one US-FNAs in correlation with surgical follow-up (SFU) were studied. statistical analysis was performed using pathology diagnosis as gold standard. Results Among 283 cases cytopathologists, 8 (2.8%) nondiagnostic (BTC I), 197 (69.6%) benign II), 31 (11%) atypical III), 14 (5%) suspicious follicular neoplasm IV), 12 (4.2%) malignancy V), 21 (7.4%) positive VI), 55 (19.4%) SFU. 368 others showed 76 (21%) BTC I, 238 (65%) II, 26 (7%) III, 10 (3%) IV, 9 (2.5%) V 5, VI, cytopathologist group achieved better sensitivity (91.3 vs.78%); slightly specificity (83.3 vs. 82%); predictive value (87.5 70%); similar negative (88.2 88%); overall accuracy (87.8 81%) compared non-cytopathologist group. Overall difference all values significant different (P = 0.041). Conclusion US-FNA a lower unsatisfactory rate significantly values. Cytopathologists may play an important role patient care. Diagn. Cytopathol. 2016;44:787–791. © 2016 Wiley Periodicals, Inc.

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