Imaging fluorometer for time resolved fluorescence
作者： Ahmad Yekta , Paul Donders , Peter Ramm , Carlos Zarate , Zahra Masoumi
DOI:
关键词:
摘要: The present invention relates to an apparatus and method for imaging time resolved fluorescence in biochemical medical samples. In a primary aspect, the device includes lens of large aperture, flash lamp illumination path, fast-acting solid state shutter or gated detector emission delivering homogenous monochromatic plurality wells distributed within microwell plate, digital camera high quantum efficiency, computer under control, is pulsed at short intervals. operates limit exposure period some microseconds after extinction each pulse, during which only delayed transmitted camera. achieves simultaneous samples, with sensitivity throughput.
lens.org 参考文章(6)
Chen-Yu Tai, Time-resolved light decay measurements without using a gated detector ,(2001)
Douglas N. Modlin, John C. Owicki, Todd E. French, Apparatus and methods for time-resolved spectroscopic measurements ,(1999)
Paul L. Edmiston, Silvia Kölchens, S. Scott Saavedra, Temporally Gating a Slow-Scan CCD with a Liquid Crystal Shutter Applied Spectroscopy. ,vol. 47, pp. 250- 253 ,(1993) , 10.1366/0003702934048389
N. P. Verwoerd, E. J. Hennink, J. Bonnet, C. R. G. Van der Geest, H. J. Tanke, Use of ferro-electric liquid crystal shutters for time-resolved fluorescence microscopy Cytometry. ,vol. 16, pp. 113- 117 ,(1994) , 10.1002/CYTO.990160204
Rolf Mueller, Timothy Ormsby, Gang Sun, Kenneth R. Castle, Peter Ramm, A digital imaging system for assays in well plates, gels and blots ,(1997)
Mikko Väisälä, Jarmo Korpi, Jarmo Nurmi, Raimo Harju, Sample imaging device for high-throughput screening by fluorescence measurements ,(1999)