Prevalence and significance of methicillin-resistant Staphylococcus aureus in patients with cystic fibrosis.

摘要: Recent reports indicate that methicillin-resistant Staphylococcus aureus (MRSA) may be emerging as a significant pediatric nosocomial pathogen. Children with cystic fibrosis (CF) pulmonary disease are subject to many of the risk factors for MRSA colonization and/or infection. We retrospectively investigated prevalence and significance from sputum throat cultures in 452 patients CF followed during 1986. No had been isolated 1984 or 1985. Although S. was 212 (47%) 1986, only 14 (3%) showed MRSA. The strains 11 different antimicrobial susceptibility patterns. Neither age, clinical condition, nor recent prior hospitalization correlated acquisition. Acquisition did not appear directly affect course these even though no patient received any treatment their is low, although factors. appears mainly community-acquired represent rather than However, potential infection present, vigilance required monitoring changes frequency isolation organisms.