Comparative study of the physicochemical properties of ortho-substituted aromatic nitroso compounds

摘要: C-Nitroso compounds represent a class of chemical species with radical spin trapping capacity. They are widely employed to scavenge nitric oxide (NO) in biological and systems prospectively could be applied reduce control NO formation from important processes. In this study, we examined the physicochemical properties four ortho-substituted aromatic nitroso compounds, 3,5-dibromo-4-nitrosobenzenesulfonate (DBNBS), 4-nitrosobenzenesulfonate (NBS), 3,5-dimethyl-4-nitrosobenzenesulfonate (DMNBS), 3,5-dichloro-4-nitrosobenzenesulfonate (DCNBS). These like most C-nitroso traps, exist monomer–dimer equilibrium, only monomeric form is active as free scavenger. The influence ring substituent(s) on dissociation dimer give monomer was investigated using UV–vis spectrophotometry. We describe thermodynamic kinetic parameters associated equilibria, which allow us provide ...