Neural mechanism of spatio-chromatic opponency in the Drosophila amacrine neurons.

摘要: Visual animals detect spatial variations of light intensity and wavelength composition. Opponent coding is a common strategy for reducing information redundancy. Neurons equipped with both spectral opponency have been identified in vertebrates but not yet insects. The Drosophila amacrine neuron Dm8 was recently reported to show color opponency. Here, we demonstrate exhibits spatio-chromatic Antagonistic convergence the direct input from UV-sensing R7s indirect broadband receptors R1-R6 through Tm3 Mi1 sufficient confer Dm8's UV/Vis (ultraviolet/visible light) Using high resolution monochromatic stimuli, pale yellow subtypes Dm8s, inheriting retinal mosaic characteristics, distinct tuning properties. 2D white-noise stimulus reverse correlation analysis, found that UV receptive field (RF) has center-inhibition/surround-excitation structure. In absence R7 inputs, polarity RF inverted owing excitatory photoreceptors R1-R6. new synGRASP method based on endogenous neurotransmitter receptors, neighboring Dm8s form mutual inhibitory connections mediated by glutamate-gated chloride channel GluClα, which essential animals' phototactic behavior. Our study shows could arise early visual stage, suggesting processing invertebrates vertebrates.