作者: John E. Olerud , Mary Ann Riederer-Henderson , Anne W. Holmes , Fred K. Forster
DOI: 10.1016/0301-5629(90)90085-Q
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摘要: Backscatter acoustic techniques at high ultrasonic frequencies (10-40 MHz) were utilized to investigate the attenuation coefficient of normal skin and relationship between healing surgical wounds ranging in age from 9 49 days. The was calculated with measurements depths 0.5 1.0 mm, primarily reticular dermis. values for control ranged 6.0 Np cm-1 10 mHz 19.6 40 MHz a corresponding slope 0.45 MHz-1. Wound initially increased wound approximately 15% day 30% 34 but did not continue increase through 49. During same period, however, total collagen (as percentage wet weight) constant rate 45% 70% Thus over time period studied may be sensitive more than content tissue. It affected by other competing factors as mature such intermolecular cross-linking, fiber bundle size, structural arrangement bundles or tissue constituents proteoglycans elastin. observations that integrated using backscatter range 10-40 substantially early wounds, beyond 34, remained significantly lower entire are agreement results an independent study transmission 100 MHz.