Is pigment cell pattern formation in zebrafish a game of cops and robbers

摘要: Biological self-organization generates enormous diversity from relatively few conserved pathways controlling differential gene expression, raising the prospect that understanding extensive biological complexity relies, in turn, upon simple regulatory frameworks. Consequently, regulation of has attracted attention, not only biologists but also physical and mathematical scientists enthused by exploring emergence complex structure from, ultimately, zygote. Pigment cell patterning, particular, presents a remarkable opportunity within these broader studies to link genotype phenotype this been exploited numerous recent investigations documenting impact genetic mutations on patterning number fish species. As ever, novel results such further challenges. Ze