Synergistic interaction between polycyclic aromatic hydrocarbons and environmental tobacco smoke on the risk of obesity in children and adolescents: The U.S. National Health and Nutrition Examination Survey 2003-2008.

作者: Hyun-Woo Kim , Sin Kam , Duk-Hee Lee

DOI: 10.1016/J.ENVRES.2014.08.032

关键词:

摘要: Abstract Background Polycyclic aromatic hydrocarbons (PAHs) may be obesogens. However, the role of PAHs independent environmental tobacco smoke (ETS) is unclear, and interaction between ETS remains unknown. Methods We performed cross-sectional analyses urinary concentrations PAH metabolites, body mass index (BMI), waist circumference (WC) in 1985 people aged 6–18 years using data from 2003–2008 U.S. National Health Nutrition Examination Survey. exposure level was measured as serum cotinine level. Results metabolites were positively associated with BMI WC both ETS-unexposed ETS-exposed groups. The adjusted odds ratios for general obesity defined by age- sex-specific BMI≥95th percentile across quartiles total 1, 4.51, 2.57, 8.09 ( P trend =0.003) group 2.02, 1.83, 3.86 Conclusion Environmental to childhood irrespective ETS. In particular, simultaneous substantially increase risk obesity.

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