The effect of nicotine on growth of Streptococcus mutans.

摘要: There is little information available concerning the effects of nicotine on oral bacteria; and in particular, Streptococcus mutans, an important microbe etiology dental caries. To test nicotine, mutans were incubated either 0 or 10(-1)-10(-7) M concentrations then plated onto mitis-salivarius-bacitracin agar. Colonies counted treatment groups compared. Both 10(-1) 10(-2) caused total inhibition bacterial growth, while 10(-3) 10(-4) produced significantly more colonies than control. Also, 10(-6) 10(-7) a significant reduction mean number colonies. These results suggest biphasic, dosage-dependent effect growth mutans. Since has been reported within saliva smokeless tobacco users, use these products could stimulate possibly place user at increased risk for