The Eye as a Model for Immune Privilege
作者： Linda D. Hazlett , Joan Stein-Streilein
DOI: 10.1007/978-3-0348-0445-5_1
关键词:
摘要: Immune privilege was first observed in the eye as early 1873 when tumors, and later skin allografts were accepted for extended periods of time eye. allows protection against infectious organisms absence inflammation. This chapter organizes our current knowledge immune homeostasis relation to health disease. review discusses role innate adaptive regulation ocular environment immunosuppressive molecules on both stromal cells. Microorganisms that cause bacterial keratitis are listed therapeutical approaches discussed.
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Carol A. Morris, Fiona Carney, Manal M. Gabriel, Elizabeth A. Szliter, Linda D. Hazlett, Development of a new extended-wear contact lens model in the rat. The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc. ,vol. 28, pp. 119- 123 ,(2002)
A W Taylor, J W Streilein, D G Yee, Suppression of nitric oxide generated by inflammatory macrophages by calcitonin gene-related peptide in aqueous humor. Investigative Ophthalmology & Visual Science. ,vol. 39, pp. 1372- 1378 ,(1998)
Medawar Pb, A second study of the behaviour and fate of skin homografts in rabbits: A Report to the War Wounds Committee of the Medical Research Council Journal of Anatomy. ,vol. 79, pp. 157- 176 ,(1945)
Pierre-Yves Mantel, Carsten B. Schmidt-Weber, Transforming Growth Factor-Beta: Recent Advances on Its Role in Immune Tolerance Methods in Molecular Biology. ,vol. 677, pp. 303- 338 ,(2010) , 10.1007/978-1-60761-869-0_21
Jonathan H. Lass, Eric Pearlman, Saloni Khatri, John Gomez, Fred P. Heinzel, Eugenia Diaconu, Carolyn M. Kalsow, W. Matthew Petroll, Regulation of Endotoxin-Induced Keratitis by PECAM-1, MIP-2, and Toll-like Receptor 4 Investigative Ophthalmology & Visual Science. ,vol. 43, pp. 2278- 2284 ,(2002)
A. W. Taylor, A. P. Prodeus, M. C. Carroll, W. R. O. Goslings, J. W. Streilein, M. J. Jager, A small molecular weight factor in aqueous humor acts on C1q to prevent antibody-dependent complement activation Investigative Ophthalmology & Visual Science. ,vol. 39, pp. 989- 995 ,(1998)
G A Wilbanks, J W Streilein, Distinctive humoral immune responses following anterior chamber and intravenous administration of soluble antigen. Evidence for active suppression of IgG2-secreting B lymphocytes. Immunology. ,vol. 71, pp. 566- 572 ,(1990)
Ruslan Medzhitov, Paula Preston-Hurlburt, Charles A. Janeway, A human homologue of the Drosophila Toll protein signals activation of adaptive immunity Nature. ,vol. 388, pp. 394- 397 ,(1997) , 10.1038/41131
David Danielpour, S. W. Cousins, M. M. McCabe, J. W. Streilein, Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor. Investigative Ophthalmology & Visual Science. ,vol. 32, pp. 2201- 2211 ,(1991)
Ernesto J. Munoz-Elias, Rosa P. Gomariz, Mario Delgado, Doina Ganea, Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide Enhance IL-10 Production by Murine Macrophages: In Vitro and In Vivo Studies Journal of Immunology. ,vol. 162, pp. 1707- 1716 ,(1999)