Effect of PEGylation on Biodistribution and Gene Silencing of siRNA/Lipid Nanoparticle Complexes

作者: Yanjie Bao , Yi Jin , Padmanabh Chivukula , Jun Zhang , Yun Liu

DOI: 10.1007/S11095-012-0874-6

关键词:

摘要: … To this end, we systematically evaluated the effect of PEG-C-DMA on gene silencing efficiency of LNPs in vitro and in vivo after systemic administration in mice. The mechanistic …

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