Convenient modular construction of medicinally important 5-acylamino-4,5-dihydroisoxazoles featuring four elements of diversity
作者： Alexandra Kulyashova , Mikhail Krasavin
DOI: 10.1016/J.TETLET.2016.08.059
关键词:
摘要: Abstract An efficient modular approach toward medicinally important 5-acylamino-4,5-isoxazolines via the 1,3-dipolar cycloaddition reaction of nitrile oxides and MCR-derived enamide building blocks is described. This results in isoxazolines containing four elements diversity utilizing two practically simple synthetic operations.
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