Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala.

摘要: The encoding view provides a parsimonious account of the multiple convergent lines evidence for ABL’s role in fear conditioning. We do not dispute notion that activation ABL can facilitate consolidation information other structures, such as hippocampus, cortical areas, or striatum (4xMechanisms emotional arousal and lasting declarative memory. Cahill, L McGaugh, J.L. Trends Neurosci. 1998; 21: 294–299Abstract | Full Text PDF PubMed Scopus (952)See all References, 27xAmygdala modulation memory systems (hippocampus caudate-putamen) . Packard, M.G Teather, L.A. Neurobiol. Learn. Mem. 69: 163–203Crossref (214)See References). Rather, we argue is involved functions structures.While believe essential to implicit learning constitutes conditioning, are proposing plasticity relevant conditioning necessarily occurs within ABL. It seems possible ABL, while essential, also part distributed network encodes For example, noted, there compelling plastic changes occur regions afferent thalamic sensory process CSs (see Weinberger 1995xRetuning brain by Weinberger, N.M. See ReferencesWeinberger 1995). Additionally, areas both efferent (e.g., perirhinal cortex, hippocampal formation, cortex) may participate with long-term fear. remains future research determine whether these representations exist and, if so, unravel their nature.‡To whom correspondence should be addressed (e-mail: fanselow@ucla.edu).