Micellar solubilization of drugs.

摘要: PURPOSE Micellar solubilization is a powerful alternative for dissolving hydrophobic drugs in aqueous environments. In this work, we provide an insight into subject. METHODS A concise review of surfactants and micelles applications pharmacy was carried out. RESULTS Initially, description micellar systems presented. Following, extensive on drug solubilization, including both the principles involved phenomenon work already done regarding by The application delivery, order to minimize degradation loss, prevent harmful side effects, increase bioavailability, also Special emphasis given more recent use polymeric micelles. Finally, briefly discuss importance as biological models well its catalysis. CONCLUSIONS As can be seen from presented, important tool that finds numerous applications.