Coupling of the HPA and HPG axes in the context of early life adversity in incarcerated male adolescents
作者： Andrew R. Dismukes , Megan M. Johnson , Michael J. Vitacco , Florencia Iturri , Elizabeth A. Shirtcliff
DOI: 10.1002/DEV.21231
关键词:
摘要: The effects of early life adversity can be observed across the lifespan, and hypothalamic-pituitary-adrenal (HPA) hypothalamic-pituitary-gonadal (HPG) axes could mechanistic intermediaries underlying this phenomenon. current study examined 50 adolescent males aged 12-18 in a maximum-security correctional treatment setting. Saliva samples were collected five times day for 2 days assayed cortisol, testosterone, DHEA. Youth completed semi-structured stress interviews self-reports child maltreatment to index adversity. When youth had higher testosterone levels, they cortisol DHEA indicating positive "coupling" HPA-HPG axes. In addition, children experiencing greater tighter coupling Additional analyses hint that may driven largely by HPG axis functioning. Results indicate is within incarcerated adolescents, especially those with greatest stress.
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