Pharmaceutical interactions between antiretroviral and antimalarial drugs used in chemoprophylaxis

摘要: Human immunodeficiency virus (HIV) is the causative agent of Acquired Immunodeficiency Syndrome (AIDS). The pandemic believed to have originated within Northern Congo basin covering large parts Democratic Republic Congo, Central African Republic, Cameroon and Gabon. Although over decades, HIV-1 has spread throughout World leaving no country unaffected, sub-Saharan Africa remains region with more than 80% all infected individuals. HIV-2 epidemic largely remained restricted West along Upper Guinean forests. Co-incident these regions highest HIV distribution a part malaria belt therefore, co-infections are common. In this review we carve out consequences transmission prevention synchronous prophylaxis during occupational or leisure travelling activities region. particular, elaborate on considering pre-existing drug resistances both, parasites viruses, when determining combination for prophylactic and, if necessary, post-expositional measures focus compatibility both medications.