Lipid immiscibility and structure of the charged membrane-water interface: A theoretical investigation of glycolipids containing bilayers

摘要: Abstract The influence of the interfacial structure binary lipid mixtures on their mixing behavior has been investigated by a simple theoretical model. Two limiting situations were considered: (a) “compact” charged interfaces (e.g. anionic' phospholipid bilayers) and (b) “diffuse” (e.g., glycolipid- or glycoprotein-containing membranes). model allows us to calculate effect adsorbed ions modulating some thermodynamic bilayer's properties such as formation miscibility gaps ionotropic shift gel liquid-crystal transition temperatures. Numeric results show that bilayers with diffuse are much less sensitive than those sharp charge boundaries.