Antioxidant flavanes from Livistona chinensis

作者: Xiaobin Zeng , Qian Qiu , Chenguang Jiang , Yuntiao Jing , Guofu Qiu

DOI: 10.1016/J.FITOTE.2011.01.017

关键词:

摘要: Three new flavanes and eight known flavonoids were isolated from the fruits of Livistona chinensis. The structure established as 2S,3S-3,5,7,3',5'-pentahydroxyflavane (1), 2R,3R-3,5,6,7,8,4'-hexahydroxyflavane (2) 2R,3R-3,5,6,7,8,3',5'-heptahydroxyflavane (3), respectively, on basis chemical spectroscopic data. antiproliferative activity against four human tumor cell lines (HL-60, Mata, HepG2 CNE-1) was evaluated. 1 had significantly effects HL-60 CNE-1 with IC(50) 0.2 ± 0.01 1.0 0.1 μM, overpowering reference compound in assay (cisplatin). Most compounds also exhibited potent antioxidant activity.

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