Hepatitis C virus infection: quality of life and side effects of treatment

作者: G.R. Foster

DOI: 10.1016/S0168-8278(99)80411-5

关键词:

摘要: Studies of the subtle symptoms associated with chronic diseases and detected by quality life questionnaires are still in their infancy. The techniques used to examine these impairments well being developed use is far from routine. There a growing body evidence show that patients hepatitis C virus (HCV) without major disease related complications do perceive themselves be unwell have significant changes physical mental being. These abnormalities cannot attributed mode acquisition infection or severity liver damage. mechanism unknown but remit following successful therapy, indicating presence plays role aetiology. require careful evaluation may sufficiently severe justify therapy absence advancing Treatment HCV significantly impairs patient's life. decision as whether an individual sufficient progressive damage one which must based on assessment individual's current future status ability tolerate therapy.

参考文章(16)
Dienstag Jl, Davis Gl, Balart La, Perrillo Rp, Bodenheimer Hc, Payne J, Carey W, Jacobson Im, Lindsay K, Schiff Er, Assessing health-related quality of life in chronic hepatitis C using the sickness impact profile Clinical Therapeutics. ,vol. 16, pp. 334- 343 ,(1994)
Anita Stewart, John Ware, Measuring Functioning and Well-Being: The Medical Outcomes Study Approach Duke University Press. ,(1992) , 10.7249/CB361
Christine M. Hunt, Jason A. Dominitz, Barbara Philips Bute, Bradford Waters, Umberto Blasi, Diane M. Williams, Effect of interferon-α treatment of chronic hepatitis C on health- related quality of life Digestive Diseases and Sciences. ,vol. 42, pp. 2482- 2486 ,(1997) , 10.1023/A:1018852309885
Marilyn Bergner, Ruth A. Bobbitt, William B. Carter, Betty S. Gilson, The Sickness Impact Profile: development and final revision of a health status measure. Medical Care. ,vol. 19, pp. 787- 805 ,(1981) , 10.1097/00005650-198108000-00001
Mark E. Johnson, Dennis G. Fisher, Andrea Fenaughty, Shelley A. Theno, Hepatitis C virus and depression in drug users The American Journal of Gastroenterology. ,vol. 93, pp. 785- 789 ,(1998) , 10.1111/J.1572-0241.1998.225_A.X
Graham Ellis, J.S Woodhead, W.T Cooke, SERUM-25-HYDROXYVITAMIN-D CONCENTRATIONS IN ADOLESCENT BOYS The Lancet. ,vol. 309, pp. 825- 828 ,(1977) , 10.1016/S0140-6736(77)92776-3
Herbert L. Bonkovsky, J. Michael Woolley, , Reduction of health-related quality of life in chronic hepatitis C and improvement with interferon therapy Hepatology. ,vol. 29, pp. 264- 270 ,(1999) , 10.1002/HEP.510290124
J. Schuling, J. Greidanus, B. Meyboom-De Jong, Measuring functional status of stroke patients with the Sickness Impact Profile Disability and Rehabilitation. ,vol. 15, pp. 19- 23 ,(1993) , 10.3109/09638289309165864
Thierry Poynard, Pierre Bedossa, Pierre Opolon, Natural history of liver fibrosis progression in patients with chronic hepatitis C The Lancet. ,vol. 349, pp. 825- 832 ,(1997) , 10.1016/S0140-6736(96)07642-8