Primordial Odontogenic Cyst with Induction Phenomenon (Zonal Fibroblastic Hypercellularity) and Dentinoid Material Versus Archegonous Cystic Odontoma: You Choose!

摘要: The most recent A.F.I.P. fascicle defines primordial odontogenic cyst (POC) as a distinct, nonkeratinized, of “undetermined origin” forming in the place developing normal or supernumerary tooth. However, majority examples reported literature under this term represent keratocysts (keratocystic tumors). In addition, there are rare cases cystic odontomas. An 18-year-old Caucasian male presented with unilocular mandibular radiolucent lesion congenitally missing molar. Histologically, it featured nonkeratinizing, thin stratified squamous epithelial lining areas spongiosis and foci vacuolization individual basal cells without significant nuclear palisading. Focally, budding cell layer was identified. A zone increased cellularity featuring induction-type fibroblasts present subepithelially well dentinoid deposits nests. Immunohistochemically, negative for calretinin induction-like S100 protein, smooth muscle actin, CD34. case externally reviewed by five oral pathologists who provided various diagnostic interpretations including cyst, not otherwise specified (NOS), ameloblastic changes, unicystic ameloblastoma. At that time, final diagnosis NOS rendered comment may true example POC odontoma. has recurred within 13 year follow-up period after initial excision. unusual is formation an archegonous