作者: Wei LI , Jing WEI , Dao-Ying CHEN , Mei-Jing WANG , Yang SUN
DOI: 10.1016/S1875-5364(20)60040-1
关键词:
摘要: Two new 2-carboxymethyl-3-hexyl-maleic anhydride derivatives, arthrianhydride A (1) and B (2), along with three known compounds 3-5, were isolated from the fermentation broth of a grasshopper-associated fungus Arthrinium sp. NF2410. The structures 1 2 determined based on analysis HR-ESI-MS NMR spectroscopic data. Furthermore, evaluated inhibitory activity against enzyme SHP2 both them showed moderate SHP2.