Ige antibodies for the treatment of cancer
作者： Christopher F. Nicodemus , Birgit C. Schultes , Tracy R. Daniels , Manuel L. Penichet , Jose A. Rodriguez
DOI:
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摘要: The present invention provides monoclonal IgE antibodies comprising Fc epsilon (e) constant regions and variable at least one antigen binding region specific for a single epitope of circulating, tumor-associated (TAA) that is not cell surface wherein the targeted highly repetitive or non-repetitive epitope. are useful in treatment cancer associated with tumor antigen. In embodiment TAA prostate-specific (PSA).
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