Contribution of Efflux Pumps, Porins, and β-Lactamases to Multidrug Resistance in Clinical Isolates of Acinetobacter baumannii

作者: C Rumbo , E Gato , M López , C Ruiz de Alegría , Felipe Fernández-Cuenca

DOI: 10.1128/AAC.00730-13

关键词:

摘要: … plays an important role in resistance to carbapenem antibiotics (39), we found that decreased expression of a porin was significantly associated with antimicrobial resistance. We …

参考文章(49)
M. Ruiz, S. Marti, F. Fernandez-Cuenca, A. Pascual, J. Vila, High prevalence of carbapenem-hydrolysing oxacillinases in epidemiologically related and unrelated Acinetobacter baumannii clinical isolates in Spain Clinical Microbiology and Infection. ,vol. 13, pp. 1192- 1198 ,(2007) , 10.1111/J.1469-0691.2007.01825.X
P. Espinal, H. Seifert, L. Dijkshoorn, J. Vila, I. Roca, Rapid and accurate identification of genomic species from the Acinetobacter baumannii (Ab) group by MALDI-TOF MS Clinical Microbiology and Infection. ,vol. 18, pp. 1097- 1103 ,(2012) , 10.1111/J.1469-0691.2011.03696.X
Jose Luis Martinez, María Blanca Sánchez, Laura Martínez-Solano, Alvaro Hernandez, Leonor Garmendia, Alicia Fajardo, Carolina Alvarez-Ortega, Functional role of bacterial multidrug efflux pumps in microbial natural ecosystems. Fems Microbiology Reviews. ,vol. 33, pp. 430- 449 ,(2009) , 10.1111/J.1574-6976.2008.00157.X
F C Tenover, R D Arbeit, R V Goering, P A Mickelsen, B E Murray, D H Persing, B Swaminathan, Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. Journal of clinical microbiology. ,vol. 33, pp. 2233- 2239 ,(1995) , 10.1128/JCM.33.9.2233-2239.1995
Kevin S. Akers, Katrin Mende, Heather C. Yun, Duane R. Hospenthal, Miriam L. Beckius, Xin Yu, Clinton K. Murray, Tetracycline Susceptibility Testing and Resistance Genes in Isolates of Acinetobacter baumannii-Acinetobacter calcoaceticus Complex from a U.S. Military Hospital Antimicrobial Agents and Chemotherapy. ,vol. 53, pp. 2693- 2695 ,(2009) , 10.1128/AAC.01405-08
Khairollah Asadollahi, Morovat Taherikalani, Abbas Maleki, Eshrat Alizadeh, Hasan Valadbaigi, Setareh Soroush, Hossain Maleki, Parisa Asadollahi, Mohammad Emaneini, Diversity of aminoglycoside modifying enzyme genes among multidrug resistant Acinetobacter baumannii genotypes isolated from nosocomial infections in Tehran hospitals and their association with class 1 integrons. Acta Microbiologica Et Immunologica Hungarica. ,vol. 58, pp. 359- 370 ,(2011) , 10.1556/AMICR.58.2011.4.11
Germán Bou, Jesús Martínez-Beltrán, Cloning, nucleotide sequencing, and analysis of the gene encoding an AmpC β-lactamase in Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy. ,vol. 44, pp. 428- 432 ,(2000) , 10.1128/AAC.44.2.428-432.2000
Jun-Ren Sun, Ming-Chin Chan, Tein-Yao Chang, Wei-Yao Wang, Tzong-Shi Chiueh, None, Overexpression of the adeB Gene in Clinical Isolates of Tigecycline-Nonsusceptible Acinetobacter baumannii without Insertion Mutations in adeRS Antimicrobial Agents and Chemotherapy. ,vol. 54, pp. 4934- 4938 ,(2010) , 10.1128/AAC.00414-10
K. M. Hujer, A. M. Hujer, A. Endimiani, J. M. Thomson, M. D. Adams, K. Goglin, P. N. Rather, T.-T. D. Pennella, C. Massire, M. W. Eshoo, R. Sampath, L. B. Blyn, D. J. Ecker, R. A. Bonomo, Rapid Determination of Quinolone Resistance in Acinetobacter spp. Journal of Clinical Microbiology. ,vol. 47, pp. 1436- 1442 ,(2009) , 10.1128/JCM.02380-08