摘要: Abstract This review details major new observations in the diagnosis and treatment of leukemias plasma cell dyscrasias that have been communicated since last version this work. is not exhaustive may appear to some be rather superficial. However, it should serve as an accurate index current thinking accomplishments. The clearly demonstrates a trend away from traditional chemotherapeutic approaches related diseases favor more rational design treatments for specific based on laboratory observations. Some refer agents resulted such approach targeted therapy suggest they represent era cancer treatment, although one first conceived, synthesized tested was 6-mercaptopurine decades ago. Furthermore, there no than surgery, which has practiced longer any us lived. At rate, whatever slogan used describe clear preclinical science ever before. chapter certainly true dyscrasias. What demonstrated yet better rationale led results. That remains proven or disproven by continued observation our treated patients.