Factors Associated With Invasive Intraductal Papillary Mucinous Carcinoma of the Pancreas.

摘要: Importance Invasive intraductal papillary mucinous carcinoma has aggressive malignant behavior, including lymph node metastasis. It is important to identify factors associated with invasive determine operative procedures, but they remain unclear. Objective To the specific neoplasms for branch duct, main and mixed type carcinomas. Design, Setting, Participants Retrospective cohort study of 286 consecutive patients who underwent surgical resection neoplasm from July 1999 December 2015 at a tertiary institute. We compared clinical features between 96 (33.6%) 190 (66.4%) noninvasive each morphological type. Main Outcomes Measures Factors carcinoma. Mural nodule size was measured by endoscopic ultrasonography. Results Of included in cohort, median (range) age 71 (28-86) years, 162 (56.6%) were male. High mural independently all types (branch duct: odds ratio [OR], 1.992; 95% CI, 1.177-3.367; P  = .01; OR, 1.443; 1.094-1.905; mixed: 1.178; 1.057-1.312; .04). The cutoff values neoplasms, determined receiver operating characteristic, 9 mm duct 6 A high carcinoembryonic antigen level pancreatic juice (OR, 1.002; 1.000-1.003; .01) .048) carcinomas, be 150 300 ng/mL, respectively (to convert micrograms per liter, multiply 1). In addition, both being female having an elevated serum carbohydrate 19-9 also found carcinoma, using any 2 among 4 identified yielded highest accuracy (79.0%) For types, these 86.0% differentiating which superior accuracies “high-risk stigmata” or “worrisome features” suggested international consensus guideline 2012 (66.1% 39.9%, respectively). Conclusions Relevance measurement carcinomas might play roles predicting further large studies are needed confirm results.