Angiogenesis inhibitors in gastric and gastroesophageal junction cancer
作者： Giandomenico Roviello , Roberto Petrioli , Luigi Marano , Karol Polom , Daniele Marrelli
DOI: 10.1007/S10120-015-0537-5
关键词:
摘要: Despite significant improvements in systemic chemotherapy during the past two decades, prognosis of patients with advanced gastric and gastroesophageal junction adenocarcinoma remains poor. Because molecular heterogeneity, it is essential to classify tumors based on underlying oncogenic pathways develop targeted therapies acting individual tumors. Unfortunately, although a number targets have been studied, very few these agents can be used clinical setting. In this review, we summarize available data anti-angiogenic advanced/metastatic cancer.
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