The peripheral perfusion index and transcutaneous oxygen challenge test are predictive of mortality in septic patients after resuscitation

摘要: The peripheral perfusion index (PI) is a noninvasive numerical value of perfusion, and the transcutaneous oxygen challenge test (OCT) defined as degree partial pressure (PtcO2) response to 1.0 FiO2. monitoring predict outcome remains be established in septic patients after resuscitation. Moreover, prognostic PI has not been investigated patients. Forty-six patients, who were receiving PiCCO-Plus cardiac output monitoring, included study group. Twenty stable postoperative studied control All inspired FiO2 for 10 minutes during OCT. Global hemodynamic variables, traditional metabolic OCT related-variables measured simultaneously at 24 hours PiCCO catheter insertion. We obtained 10min-OCT ((PtcO2 on oxygen) - (baseline PtcO2)), ((10min-OCT)/(PaO2 baseline PaO2)) was significantly correlated with PtcO2, (OCI) all group had higher than shock In sepsis group, macro parameters ScvO2 showed no differences between survivors nonsurvivors. nonsurvivors lower PI, OCI, arterial lactate level. OCI predicted ICU mortality an accuracy that similar A <0.2 <66mmHg related poor are predictive Further investigations required determine whether correction impaired level may improve