The ensemble nature of allostery

作者: Hesam N. Motlagh , James O. Wrabl , Jing Li , Vincent J. Hilser

DOI: 10.1038/NATURE13001

关键词:

摘要: … Indeed, more recent discoveries emphasize how nature uses the full spectrum of conformational heterogeneity 19 (for example, rigid body movement 20,21,22 , folded yet dynamic …

参考文章(108)
Arthur G. Palmer, Christopher D. Kroenke, J. Patrick Loria, Nuclear magnetic resonance methods for quantifying microsecond-to-millisecond motions in biological macromolecules. Methods in Enzymology. ,vol. 339, pp. 204- 238 ,(2001) , 10.1016/S0076-6879(01)39315-1
Giovanni Cesareni, Mario Gimona, Modular protein domains Wiley-VCH. ,(2005)
Erik R. P. Zuiderweg, Eric B. Bertelsen, Aikaterini Rousaki, Matthias P. Mayer, Jason E. Gestwicki, Atta Ahmad, Allostery in the Hsp70 chaperone proteins. Topics in Current Chemistry. ,vol. 328, pp. 99- 153 ,(2012) , 10.1007/128_2012_323
William A. Eaton, Eric. R. Henry, James Hofrichter, Andrea Mozzarelli, Is cooperative oxygen binding by hemoglobin really understood Nature Structural & Molecular Biology. ,vol. 6, pp. 351- 358 ,(1999) , 10.1038/7586
M.M. Silva, P.H. Rogers, A Arnone, A third quaternary structure of human hemoglobin A at 1.7-A resolution. Journal of Biological Chemistry. ,vol. 267, pp. 17248- 17256 ,(1992) , 10.1016/S0021-9258(18)41919-9
Chung-Jung Tsai, Antonio del Sol, Ruth Nussinov, Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms Molecular BioSystems. ,vol. 5, pp. 207- 216 ,(2009) , 10.1039/B819720B
A. B. Ward, A. Sali, I. A. Wilson, Integrative Structural Biology Science. ,vol. 339, pp. 913- 915 ,(2013) , 10.1126/SCIENCE.1228565
Gregory Manley, Ivan Rivalta, J. Patrick Loria, Solution NMR and computational methods for understanding protein allostery. Journal of Physical Chemistry B. ,vol. 117, pp. 3063- 3073 ,(2013) , 10.1021/JP312576V
Charles K Fisher, Collin M Stultz, Constructing ensembles for intrinsically disordered proteins Current Opinion in Structural Biology. ,vol. 21, pp. 426- 431 ,(2011) , 10.1016/J.SBI.2011.04.001
Chun Tang, John M. Louis, Annie Aniana, Jeong-Yong Suh, G. Marius Clore, Visualizing transient events in amino-terminal autoprocessing of HIV-1 protease Nature. ,vol. 455, pp. 693- 696 ,(2008) , 10.1038/NATURE07342