A new homoisoflavonoid and the bioactivities of some selected homoisoflavonoids from the inter-bulb surfaces of Scilla nervosa subsp. rigidifolia

摘要: Abstract Seven homoisoflavonoids and one stilbenoid, 3-(4′-methoxybenzyl)-6,7-dihydroxy-5-methoxychroman-4-one (1) which is new; 3-(4′-methoxybenzyl)-6-hydroxy-5,7-dimethoxychroman-4-one (2); 3-(4′-methoxybenzyl)-5,7-dimethoxychroman-4-one (3); 3-(3′-hydroxy-4′-methoxybenzyl)-5,7-dimethoxychroman-4-one (4); 3-(4′-methoxybenzylidene)-5,7-dihydroxy-6-methoxychroman-4-one (5); 3-(4′-hydroxybenzylidene)-5,7-dihydroxy-6-methoxychroman-4-one (6); 3-(4′-hydroxybenzylidene)-5,7-dihydroxychroman-4-one (7) 4,3′,5′-trihydroxy-3-methoxystilbene (8), were isolated from the yellow inter-bulb deposits Scilla nervosa. The structures of these compounds elucidated by 1D- 2D-NMR mass spectrometry. A number extracts, fractions tested displayed bacterostatic activity with MICs ranging between 0.156 1.250 mg/ml. Two extracts significant α-glucosidase inhibitory a showed strong antioxidant with, 1, 2 8 displaying lower MECs than positive control ascorbic acid (0.0156 mg/ml).