Influence of body mass index on pediatric urolithiasis

摘要: Summary Objective In recent years, there has been increased incidence of urolithiasis in children. Changing nutritional patterns and sedentary lifestyles predispose to urolithiasis, as well the global rise obesity. It established that prevalence high body mass index (BMI) is increasing pediatric population. The aim present study was incorporate 24-h urine metabolic analysis results with BMI values evaluate tendency towards stone formation Methods Eighty-four children were recruited study, stratified into three categories low, normal, or upper. All patients evaluated results. Patients a secondary cause such hyperparathyroidism, cystinuria, primary hyperoxaluria, inflammatory bowel disease, cystic fibrosis, history prematurity and/or use drug, recurrent urinary tract infection, anomaly excluded. Additionally, it ensured none taking specific medication diet could alter their acid-base metabolism calcium, oxalate, uric acid levels. Results Mean 21.6 ± 2.9 kg/m 2 . LBMI found 52 (61.9%), N-BMI 20 (23.8%), U-BMI 12 (14.3%) patients. No significant differences between groups for sizes numbers. patients' characteristics parameters are presented Table. Discussion literature, several studies have focused on relationship obesity disease. However, only few We encountered different from mainly adult some studies. Our shows not under greater risk than other groups. An important portion our group L-BMI group; nevertheless we cannot conclude having low predisposes based evaluation factors rather groups, according analysis. Conclusion indicate itself be considered separate definite factor development Although mechanisms causative better defined adults, further investigating these warranted. Table Patients' mean ± SD p Sex  Male 28 8 6 0.575  Female 24 Age (years) 6.9 ± 4.0 9.2 ± 4.5 9.4 ± 5.5 0.071 (kg/m ) 15.5 ± 1.6 20.8 ± 1.5 30.1 ± 2.9 Stone number 1.6 ± 1.0 2.0 ± 1.5 1.7 ± 0.8 0.709 size (mm) 13.7 ± 10.2 13.8 ± 10.5 13.0 ± 9.6 0.951 Ca (mg/kg/24 h) 3.7 ± 3.0 4.2 ± 3.9 1.3 ± 0.9 0.021 Citrate (mg/1.73 m /24 h) 362 ± 442 461 ± 391 622 ± 450 0.057 Uric 4.6 ± 4.0 3.2 ± 2.7 1.8 ± 1.4 0.017 Oxalate 7.4 ± 10.6 12.0 ± 12.4 9.9 ± 6.2 0.003 Magnesium 4.0 ± 3.3 3.3 ± 2.1 3.2 ± 2.2 0.609 Sodium (mmol/24 h) 91.3 ± 46.9 108.2 ± 76.1 88.3 ± 45.9 0.897 Difference