A retrospective comparison of androgen deprivation (AD) vs. no AD among low-risk and intermediate-risk prostate cancer patients treated with brachytherapy, external beam radiotherapy, or radical prostatectomy
作者： Jay P. Ciezki , Eric A. Klein , Kenneth Angermeier , James Ulchaker , Nabil Chehade
DOI: 10.1016/J.IJROBP.2004.05.067
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摘要: Purpose To examine the value of androgen deprivation (AD) in curative treatment low- and intermediate-risk prostate cancer treated with three major modalities: radical retropubic prostatectomy (RRP), external beam radiotherapy (EBRT), permanent implantation (PI). Methods materials During 1996–2001, 1668 patients were at The Cleveland Clinic Foundation. Only a minimum 2 years prostate-specific antigen follow-up included analysis, biochemical relapse-free survival (bRFS) was used as endpoint. Patients grouped according to modality stratified use AD. Results overall 5-year bRFS rate 87.8%. for low-risk 89% 79%. For patients, rates by (without AD vs. AD, respectively) PI: 90% 93%; EBRT: RRP: 84%. 88% 82%; 81% 84%; 75% 72%. None comparisons within risk groups or among modalities supports an increased efficacy Conclusion Five-year are not improved
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sci-hub.se 参考文章(9)
Anthony V. D'Amico, How to compare results after surgery or radiation for localized prostate carcinoma. Cancer. ,vol. 95, pp. 2041- 2043 ,(2002) , 10.1002/CNCR.10912
Mohamed A Elshaikh, Kenneth Angermeier, James C Ulchaker, Eric A Klein, Mark A Chidel, Stephen Mahoney, D.Allan Wilkinson, Chandana A Reddy, Jay P Ciezki, Effect of anatomic, procedural, and dosimetric variables on urinary retention after permanent iodine-125 prostate brachytherapy Urology. ,vol. 61, pp. 152- 155 ,(2003) , 10.1016/S0090-4295(02)02142-8
Patrick A Kupelian, Jeffrey C Buchsbaum, Mohamed A Elshaikh, Chandana A Reddy, Eric A Klein, Improvement in relapse-free survival throughout the PSA era in patients with localized prostate cancer treated with definitive radiotherapy: year of treatment an independent predictor of outcome. International Journal of Radiation Oncology Biology Physics. ,vol. 57, pp. 629- 634 ,(2003) , 10.1016/S0360-3016(03)00630-8
ALFREDO BERRUTI, LUIGI DOGLIOTTI, CARLO TERRONE, STEFANIA CERUTTI, GIANCARLO ISAIA, ROBERTO TARABUZZI, GIUSEPPE REIMONDO, MAURO MARI, PAOLA ARDISSONE, STEFANO DE LUCA, GIUSEPPE FASOLIS, DARIO FONTANA, SALVATORE ROCCA ROSSETTI, ALBERTO ANGELI, , Changes in Bone Mineral Density, Lean Body Mass and Fat Content as Measured by Dual Energy X-Ray Absorptiometry in Patients With Prostate Cancer Without Apparent Bone Metastases Given Androgen Deprivation Therapy The Journal of Urology. ,vol. 167, pp. 2361- 2367 ,(2002) , 10.1016/S0022-5347(05)64985-3
Frank A. Vicini, Alvaro Martinez, Gerald Hanks, Alex Hanlon, Brian Miles, Ken Kernan, David Beyers, Haakon Ragde, Jeffrey Forman, James Fontanesi, Larry Kestin, Gyorgy Kovacs, Louis Denis, Kevin Slawin, Peter Scardino, An interinstitutional and interspecialty comparison of treatment outcome data for patients with prostate carcinoma based on predefined prognostic categories and minimum follow-up† Cancer. ,vol. 95, pp. 2126- 2135 ,(2002) , 10.1002/CNCR.10919
MICHAEL G. OEFELEIN, Health Related Quality of Life Using Serum Testosterone as the Trigger to Re-Dose Long Acting Depot Luteinizing Hormone-Releasing Hormone Agonists in Patients with Prostate Cancer The Journal of Urology. ,vol. 169, pp. 251- 255 ,(2003) , 10.1016/S0022-5347(05)64079-7
Miljenko V. Pilepich, William T. Sause, William U. Shipley, John M. Krall, Colleen A. Lawton, David Grignon, Muhyi Al-Sarraf, Ross A. Abrams, Richard Caplan, Madhu J. John, Marvin Rotman, James D. Cox, R.L. Scotte Doggett, Philip Rubin, Mark S. Soloway, Androgen deprivation with radiation therapy compared with radiation therapy alone for locally advanced prostatic carcinoma: a randomized comparative trial of the radiation therapy oncology group Urology. ,vol. 45, pp. 616- 623 ,(1995) , 10.1016/S0090-4295(99)80053-3
Michel Bolla, Dionisio Gonzalez, Padraig Warde, Jean Bernard Dubois, René-Olivier Mirimanoff, Guy Storme, Jacques Bernier, Abraham Kuten, Cora Sternberg, Thierry Gil, Laurence Collette, Marianne Pierart, Improved Survival in Patients with Locally Advanced Prostate Cancer Treated with Radiotherapy and Goserelin The New England Journal of Medicine. ,vol. 337, pp. 295- 300 ,(1997) , 10.1056/NEJM199707313370502
AMERICANSOCIETYFORTHERAPEUTICR, Consensus statement: Guidelines for PSA following radiation therapy1 International Journal of Radiation OncologyBiologyPhysics. ,vol. 37, pp. 1035- 1041 ,(1997) , 10.1016/S0360-3016(97)00002-3