Telomerase activity in human cancer

作者: Jerry W. Shay , Woodring E. Wright

DOI: 10.1097/00001622-199601000-00012

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摘要: The chromosome ends are specialized nucleoprotein structures called telomeres, which essential for stable maintenance. In tumor-derived cell lines telomeres maintained by the ribonucleoprotein enzyme telomerase. Telomerase activity is repressed in almost all normal human somatic c

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